Значения термина mitochondrial fission на английском

Until very recently, only a single mitochondrial fission protein had been identified.

Here we show that activation-induced ROS generation is dependent on mitochondrial fission.

Altered mitochondrial fission and fusion is implicated in several neurodegenerative disorders.

MTP18 deficiency reduces mitochondrial fission and suppresses cardiomyocyte apoptosis and MI.

MFACR knockdown in cardiomyocytes and mice attenuates mitochondrial fission and MI.

This study analysed the relationship between mitochondrial fission and regulation of plant cell death.

However, the regulation of mitochondrial fission in neurons exposed to lethal stress is largely unknown.

Areas covered: In this review, the authors outline the mechanisms of mitochondrial fission and fusion.

Aberrant mitochondrial fission plays a pivotal role in the pathogenesis of skeletal muscle insulin resistance.

Promoting mitochondrial fission during HIV infection of the CNS may restore mitochondrial biogenesis and prevent neurodegeneration.

The dynamics of mitochondria were regulated by PM2.5 via facilitating mitochondrial fission.

Direct visual observation of mitochondrial fission and fusion events, together with computational approaches promise to provide new insight.

Together, these findings provide evidence that impaired mitochondrial fission contributes to neurodegeneration in this in vivo model of HSP.

Unlike other mitochondrial fission factors, GDAP1 overexpression or knockdown does not influence the susceptibility of cells to apoptotic stimuli.

For example, during infections, mitochondrial fission and fusion coincide with effector and memory T-cell differentiation, respectively, resulting in metabolic reprogramming.

In conclusion, we describe a novel signalling pathway that links TCR-induced nitric oxide release to mitochondrial fission and oxidative signalling.